farnesyltransferase inhibitor — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T2678	LB42708		Transferase
	LB42708 is an orally active farnesyltransferase (FTase) inhibitor (IC50: 0.8/1.2/2.0 nM toward H/N/K-ras).		Transferase
T38050	CP-609754		Transferase
	CP-609754 (LNK-754) is a potent and reversible farnesyltransferase inhibitor with potential anticancer activity.The IC50 for inhibiting farnesylation of recombinant human H-Ras is 0.57 ng/mL and recombinant K-Ras is 46 n...		Transferase
T17102	Tipifarnib (S enantiomer)	Tipifarnib S enantiomer,(S)-(-)-R-115777,(S)-Tipifarnib,IND-58359 S enantiomer	Transferase
	Tipifarnib S enantiomer ((S)-(-)-R-115777) is the S-enantiomer of Tipifarnib. Tipifarnib is a potent and specific farnesyltransferase inhibitor (IC50: 0.6 nM).		Transferase
T27773L	L-739750 2HCl	L-739750 2HCl(160141-08-2 Free base)	Transferase
	L-739750 2HCl is a potent inhibitor of peptidomimetic farnesyltransferase, a novel pseudopeptide mimetic with potential anticancer activity.		Transferase
T2700	FTI-277 hydrochloride	FTI 277 HCl	Apoptosis , Transferase , Ras
	FTI-277 hydrochloride (FTI 277 HCl) is an effective and specific farnesyltransferase (FTase) inhibitor (IC50: 500 pM); this selectivity is about 100-fold than the closely related GGTase I.		Apoptosis , Transferase , Ras
T10512	Prenyl-IN-1		Transferase
	Prenyl-IN-1 is a potent and selective prenylation inhibitor of geranylgeranyltransferase or farnesyltransferase.Prenyl-IN-1 shows anti-oxidative stress effects in a Parkinson's model. Prenyl-IN-1 showed anti-oxidative st...		Transferase
T24351	L 731735	L-731,735,L731735,L-731735,L731,735,L 731,735
	L 731735 is a farnesyltransferase inhibitor.
T24273	Kurasoin B	Kurasoin-B
	Kurasoin B is an inhibitor of protein farnesyltransferase.
T27773	L-739750
	L-739,750 is an inhibitor (FTI) of peptidomimetic farnesyltransferase.
T71375	FTI-2600
	FTI-2600 is a farnesyltransferase inhibitor.
T24350	L 731734	L-731,734,L 731,734,L731734,L731,734,L-731734
	L 731734 is a farnesyltransferase inhibitor.
T15770	(Rac)-CP-609754	LNK754	Influenza Virus
	LNK754 is a farnesyltransferase inhibitor. It is used for the treatment of cancer and Alzheimer's disease.		Influenza Virus
T40331	Ftase inhibitor III
	Ftase Inhibitor III, derived from a phenotypic screen, functions as an anion-dependent inhibitor of Farnesyltransferase.
T70372	FTI-249
	FTI-249 is a Farnesyltransferase inhibitor, which potently inhibited FTase (IC50 = 100Â–200 nM).
T25939	Pepticinnamin E
	Pepticinnamin E is a naturally occurring bisubstrate farnesyltransferase inhibitor.
T11331L	FTI 276		Others
	FTI-276 is an inhibitor of protein farnesyltransferase (PFT) (IC50s: 0.9 and 0.5 nM for Plasmodium falciparum and human).		Others
T70554	Chaetomellic acid A
	Chaetomellic acid A is a potent inhibitor of farnesyltransferase in isolated enzyme assays (IC50=55nM) but is inactive in whole cells. Inhibition of farnesyltransferase is selective over geranylgeranyltransferase I and I...
T70405	L-744832
	L-744832, also known as L-744,832, is a potent Farnesyltransferase inhibitor with potential anticancer activity.
T68923	FTI-2628
	FTI-2628 is a novel inhibitor of protein farnesyltransferase (FT), inhibiting the growth of P. falciparum in red blood cells and suppressing parasitemia.
T69710	LB42908
	LB42908 is a highly potent Ras farnesyltransferase inhibitor(IC(50)=0.9 nM against H-Ras and 2.4 nM against K-Ras) with potential anticancer activity.